A clever new imaging technique discovered at the University of
California, Berkeley, reveals a possible plan of attack for many
bacterial diseases, such as cholera, lung infections in cystic fibrosis
patients and even chronic sinusitis, that form biofilms that make them
resistant to antibiotics.
By devising a new fluorescent labeling strategy and employing
super-resolution light microscopy, the researchers were able to examine
the structure of sticky plaques called bacterial biofilms that make
these infections so tenacious. They also identified genetic targets for
potential drugs that could break up the bacterial community and expose
the bugs to the killing power of antibiotics.
“Eventually, we want to make these bugs homeless,” said lead
researcher Veysel Berk, a postdoctoral fellow in the Department of
Physics and the California Institute for Quantitative Biosciences (QB3)
at UC Berkeley.
Read more here.